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Immunohistochemical Examination of E-Cadherin in the Head and Neck Squamocellular Carcinomas

Scientific Research An Academic Publisher. Cancer Research, 51, Biochemical and Biophysical Research Communications, Annual Review of Immunology, 18, Journal of Cranio-Maxillo-Facial Surgery, 34, Journal of Clinical Oncology, 22, Journal of Clinical Periodontology, 33, Journal of Oral Science, 47, Integrative Cancer Therapies, 3, Nature Reviews Cancer, 9, Laboratory Investigation, 82, Relations with Clinical Variables.


British Journal of Oral and Maxillofacial Surgery, 51, Anticancer Research, 20, The paper is not in the journal. ABSTRACT Facial is present in the epithelial cells and its aberrant expression is correlated with different kinds of head and neck squamocellular carcinomas.

The purpose of the present study was to identify the expression particularities of analyzed E-cadherin in rapport compediu the localization and the differentiation of various head and neck squamocellular carcinomas.

Immunoreactions for E-cadherin in the tumoral cells were examined according to ocmpendiu score: The immunohistochemical staining indicated the presence of 12 cases of well-differentiated squamocellular carcinoma 7 cases with score 3, 3 cases with score 2 and 1 case with score 1. Moderately-differentiated carcinomas were observed in the 3 cases 2 with score 2 and 1 with score 1.

The poorly-differentiated histopathological type was present in 3 cases all with score 1.

Three types of E-cadherin distribution patterns were found: The presence of maximum score value 3 of E-cadherin was found in well-differentiated vaciala carcinomas of laryngeal, tongue, lip, nasal pyramid, and zygomatic area origin. A lower value of the score was present in the less differentiated histopathological type.


Conflicts of Interest The authors declare no conflicts of interest. Cite this paper Vasca, E. References [ 1 ] Schipper, H. Please enable JavaScript to view the comments powered by Disqus.